Abstract: Objective To study and analyze the characteristics and rules of the incidence of adverse drug reactions (ADR) reported in Fu Wai Hospital so as to provide references for rational drug use. Methods A total of 228 ADR reports collected from Jan. 2006 to Dec.2010 were described and analyzed retrospectively in respect of patients' gender,age, drug categories and clinical manifestation, etc. Results The male-female ratio among 228 ADR cases was 1:1.38 and 106 kinds of drugs were involved in, including various cardiovascular drugs, antibiotics, proprietary Chinese medicine, etc. ADR induced by cardiovascular drugs, such as antihypertension medication, antithrombotic, lipidlowering drugs and contrast medium used in coronarography occupied larger proportion. The clinic manifestation of serious ADR(SADR) was various. Among SADR cases, the number of cases who got allergic reaction induced by contrast agent was largest, one of which died. Conclusion It is important to analyze the ADR reports and feed back the related information to clinic, which is one of the important pathways to monitor ADR and reduce the ADR incidence.

Key words: adverse drug reaction, analysis, monitoring