Chinese Journal of Pharmacovigilance ›› 2012, Vol. 9 ›› Issue (1): 47-50.

• Orginal Article • Previous Articles     Next Articles

Analysis of 412 ADR/ADE Cases of Asarone Injection

XIA Xu-dong, GONG Li-xiong, XIA Ming, CHEN Chao, LIU Chao   

  1. Henan Food and Drug Reevaluation Center, Henan Zhengzhou 450004, China
  • Received:2011-08-19 Online:2012-01-10 Published:2015-08-10

PDF (PC)

325

Abstract: Objective By analyzing 412 ADR/ADE reports of Asarone injection, the general laws and features of the reaction occurrences were discussed to provide reference for rational use of medicines in clinical trials. MethodsRelevant data was collected from database of Henan ADR Monitoring Center, statistical reviewed and analyzed,from 2006 to 2010. Results

Resultsshowed the main ADR/ADE damages were skin and its attachment, which counts 184 cases(26.44%), besides, 171 stomach and intestines cases(24.57%), 111 for systemic cases(15.95%). The common serious reactions were showed as dyspnea, cyanosis, anaphylactic shock and chest distress, etc. ConclusionThus, it is important to pay attention to the ADR/ADE caused by Asarone injections, in order to improve rational use of medicines in clinical, complete drug instructions, prevent serious adverse drug reactions taking place, ensuring clinical medication safety.

Key words: Asarone injection, adverse drug reaction, anaphylactic shock, analysis