Abstract: Objective To explore the role of clinical pharmacists in the formulation of an anti infective program for diabetic foot infection and in the adjustment of the program in the process of diagnosis and treatment, and the importance of pharmaceutical care. Methods Four clinical pharmacists participated in the anti infection treatment of a patient with diabetic foot infection and diabetic nephropathy caused by Proteus penneri. The pharmacists found that Proteus penneri was naturally resistant to tegacycline by inquiring about the patient’s medical history and consulting clinical guidelines before they shifted to cefoperazone sodium and sulbactam sodium according to the drug sensitivity. The pharmacists also assisted the clinicians in providing individualized drug delivery programs and pharmaceutical care for patients. Results The clinical pharmacists adjusted the anti infection scheme of the diabetic foot quickly, the infection index of the patient returned to normal, new granulation tissue was gradually formed at the infection site, the therapeutic effect was pronounced, and the patient was discharged. Conclusion The participation of clinical pharmacists in anti infection treatment of and pharmaceutical care for a patient with diabetic foot infection and diabetic nephropathy caused by Proteus penneri can help to reduce adverse reactions, optimize the effects of medications, and rationalize clinical drug use.

Key words: Diabetic Foot Infection, Proteus penneri, Diabetic Nephropathy, Adverse Drug Reaction, Pharmaceutical Care, Clinical Pharmacist