Analysis of 32 Cases of Adverse Drug Reaction Caused by Cervus and Cucumis Polypeptide Injection

Abstract

Abstract: Objective To explore the clinical characteristics, regular and reasons of adverse drug reactions(ADR) caused by cervus and cucumis polypeptide injection. To provide references for rational use of clinical drug. Methods 32 cases of ADR caused by cervus and cucumis polypeptide injection were collected by searching for CNKI. The cases of ADR were retrospectively analyzed. Results There were 22 cases(68.75%) of males and 10 cases(31.25%) of female. And there were 3 cases(9.37%) with hypersensitiveness history and not known 6 cases(18.75%). ADR appearing within 30 min accounted for 81.25% of the total number of cases. The reports involving the respiratory system was the most accounted for 22.90%. The ADR reports of single medication accounted for 87.5% of the total number of cases. Conclusion ADR caused by a variety of factors. General attention should be paid to anaphylactic shock. Cervus and cucumis polypeptide injection should be used with more caution and exact monitoring.

Key words: cervus and cucumis polypeptide injection, adverse drug reactions(ADR), anaphylactic shock

CLC Number:

R944.11

YU Da-Hai, CHENG Mei, LI Bei. Analysis of 32 Cases of Adverse Drug Reaction Caused by Cervus and Cucumis Polypeptide Injection[J]. Chinese Journal of Pharmacovigilance, 2011, 8(6): 373-375.

References

[1] 徐卫峰.鹿瓜多肽静脉滴注致过敏性休克[J].药物不良反应杂志,2010,12(3):200.
[2] 张春玲,阮振寰．鹿瓜多肽致变态反应1例[J].西北药学杂志,2010,25(4):280.
[3] 段晋宁.鹿瓜多肽致过敏性休克1例分析[J].中国误诊学杂志,2010,10(10):2495-2496.
[4] 胡晓颖.鹿瓜多肽注射剂致速发型变态反应1例[J].现代中西医结合杂志,2008,17(27):4314.
[5] 刘铖,蒋俊杰,沈炳香.鹿瓜多肽注射液静脉滴注出现过敏性休克[J].药物不良反应杂志,2008,10(1):70-71.
[6] 董开宥,苏琼芬.鹿瓜多肽注射液致高热2例[J].药物不良反应杂志,2006,8(2):132-133.
[7] 耿丽芬,马华,李振彬.注射用鹿瓜多肽致过敏反应一例[J].华北国防医药,2008,20(5):92.
[8] 陈小蕾.注射用鹿瓜多肽致过敏性休克1例[J].药事管理,2009,6(6):370.
[9] 张志飞,李丽荣,张侠南.注射用鹿瓜多肽致过敏性反应1例[J].护理研究,2009,23(3):810.
[10] 张建良.注射用鹿瓜多肽致过敏性休克1例[J].中国药物警戒,2010,7(9):569.
[11] 李颖,汪永忠.注射用鹿瓜多肽引起过敏反应2例[J].Chin J Phar-maeoepidemiol,2010,19(2):116.
[12] 李虹影,孙霄龙.鹿瓜多肽注射液致过敏性休克2例[J].药物流行病学杂志,2009,18(5):383-384.
[13] 程静,邢军,亓翠菊.注射用鹿瓜多肽致过敏性休克1例[J].中国医院药学杂志,2007,27(9):1333.
[14] 袁青,黄丹妮,望会林.注射用鹿瓜多肽致过敏性休克1例[J].实用医学杂志,2009,25(20):3505.
[15] 业华仙.注射用鹿瓜多肽致过敏性休克1例[J].中国煤炭工业医学杂志,2010,13(1):132.
[16] 尹晓飞,李慧.注射用鹿瓜多肽致过敏性休克1例[J].药物流行病学杂志,2009,18(2):122.
[17] 祝崇雪,鲍仕慧.鹿瓜多肽注射液致过敏反应1例[J].药物流行病学杂志,2007,16(3):183.
[18] 郑美华.注射用鹿瓜多肽不良反应原因分析与护理对策[J].现代中西医结合杂志,2007,16(18):2563.
[19] 孔飞飞,谭兴起,郭良君.注射用鹿瓜多肽致不良反应7例分析[J].中国药师,2010,13（2）:261-262.
[20] 丁海波,田丽平.低分子右旋糖酐致过敏性休克的临床研究[J].现代护理,2004,10(2):112.