Two Cases of Ceftriaxone Sodium for Injection Induced Immune Hemolytic Anemia in Children

doi:10.19803/j.1672-8629.20240492

Abstract

Abstract: Objective To explore the clinical characteristics and mechanism of adverse drug reactions caused by ceftriaxone in children with immune hemolytic anemia. Methods Two cases of ceftriaxone sodium induced adverse reactions in children with immune hemolytic anemia and the correlations with adverse reactions were analyzed. Results Correlation analysis showed that both cases of hemolytic anemia were caused by ceftriaxone sodium, which was immediately discontinued and the patients were discharged after blood transfusion and glucocorticoid treatment. Conclusion Clinicians should pay attention to the risk of adverse reactions of ceftriaxone-induced immune hemolytic anemia in clinical practice. Rapid identification and appropriate immunological diagnosis and treatment can facilitate the prognosis of patients.

Key words: Ceftriaxone, Immune Hemolytic Anemia, Abdominal Pain, Anaphylactic Shock, Adverse Drug Reaction, Anti-Ceftriaxone Antibody, Serological Test, Children

CLC Number:

R978
R994.11

DING Yiqiang, LYU Zhiying, LIU Canghai, WEN Qinqin, FANG Xiaoping. Two Cases of Ceftriaxone Sodium for Injection Induced Immune Hemolytic Anemia in Children[J]. Chinese Journal of Pharmacovigilance, 2024, 21(11): 1306-1308.

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https://zgywjj.magtechjournal.com/EN/Y2024/V21/I11/1306

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