Chinese Journal of Pharmacovigilance ›› 2024, Vol. 21 ›› Issue (11): 1309-1311.
DOI: 10.19803/j.1672-8629.20240482

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One Case of Anaphylaxis Caused by Magnesium Isoglycyrrhizinate Injection

JIANG Nan1, WANG Kun2, ZHANG Gangping3, XING Ruimin1, WANG Haiye1,*   

  1. 1Department of Pharmacy, Handan Central Hospital, Handan Hebei 056002, China;
    2Pharmacovigilance Center of Hebei, Shijiazhuang Hebei 050000, China;
    3Drug Monitoring Center of Handan, Handan Hebei 056002, China
  • Received:2024-07-12 Online:2024-11-15 Published:2024-11-20

Abstract: Objective To analyze the etiology and characteristics of anaphylaxis induced by magnesium isoglycyrrhizinate injection so as to provide references for clinical safe use. Methods One case of anaphylaxis caused by intravenous drip of magnesium isoglycyrrhizinate injection was analyzed. The adverse reactions of magnesium isoglycyrrhizinate injection and the pathogenesis of anaphylaxis were reviewed. Results The chances of anaphylaxis being induced by magnesium isoglycyrrhizinate injection were considered high. After active anti-allergic therapy and symptomatic support therapy, the symptoms of anaphylaxis gradually subsided and improved. Conclusion When magnesium isoglycyrrhizinate injection is used, clinicians ought to be alert to the risk of adverse reactions and severe allergic reactions, especially among patients with a history of allergy, and be ready to take precautions.

Key words: Magnesium Isoglycyrrhizinate, Injection, Allergic Shock, Pharmacovigilance, Adverse Drug Reaction

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