Abstract: Objective We probe into the status, characteristics and influencing factors of ADR cases induced by antibiotics, for providing a reference for clinical treatment of children. Methods In the retrospective statistical analysis study, a total of 397 ADR cases induced by antibiotics in 2009 were analyzed and evaluated in respects of their age, drug varieties, organs and system involved and departments. Results Of the total 397 ADR cases, the highest proportion was in the early childhood, up to 39.88%. Generation and second generation cephalosporin were used mostly, 31.23% and 30.73% respectively. Lesions of skin and its appendages were the most common presentations of the ADR, up to 88.92%; the ADR cases which were from outpatient were at most, up to 92.44%. Conclusion As Children's Hospital, we should pay more attention on the this problems of drugs uscd in children. So it is necessary to raise the awareness of ADR reporting system for doctors and nurses to improve the level of monitoring of adverse reactions. Ultimately, we can improve the healthcare quality.

Key words: Adverse Drug Reactions(ADR), antibiotics, analysis