Chinese Journal of Pharmacovigilance ›› 2025, Vol. 22 ›› Issue (2): 183-187.
DOI: 10.19803/j.1672-8629.20240212

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Acceptance of Traditional Chinese Medicines in Patients with Ulcerative Colitis: a Multicenter Cross-Sectional Study

BU Zhijun1, LIU Fang2, HOU Wenbin1, SU Juanping3, LIU Yandi4, SU Xiaolan5, WANG Jianyun6, LI Junxiang7, SUN Yuxin1, CHEN Yunru1, ZHENG Youyou1, WANG Xuehui1, LIU Fengshuang8, TIAN Yuanchun9, LIU Jianping1, LIU Zhaolan1,*   

  1. 1Center for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    2Department of Gastroenterology, China-Japan Friendship Hospital, Beijing 100029, China;
    3Department of Spleen and Gastroenterology, Shanxi Provincial Hospital of Traditional Chinese Medicine, Taiyuan Shanxi 030012, China;
    4Department of Gastroenterology, Tianjin People's Hospital, Tianjin 300122, China;
    5Department of Spleen and Stomach Diseases, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China;
    6Department of Spleen and Stomach Diseases, the Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 100078, China;
    7Department of Spleen, Stomach and Hepatobiliary, East Hospital, Beijing University of Chinese Medicine, Beijing 100078, China;
    8College of Acupuncture, Moxibustion and Orthopedics, Hubei University of Chinese Medicine, Wuhan Hubei 430065, China;
    9College of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Wuhan Hubei 430065, China
  • Received:2024-03-30 Online:2025-02-17 Published:2025-02-17

Abstract: Objective To assess the level of acceptance of traditional Chinese medicine (TCM) among outpatients with ulcerative colitis (UC) and to find out what shapes their decision to accept or decline TCM treatment. Methods A survey was conducted among UC outpatients at various hospitals in Beijing. The collected data was analyzed using Statistical Package for the Social Sciences (SPSS) version 26.0. Results The survey yielded 236 questionnaires, with 208 valid responses. The median age of the participants was 40 years (interquartile range: 32, 50), comprising 123 males (59.13%) and 85 females (40.87%). Multivariable logistic regression revealed that gender [Odds Ratio (OR)=2.53, 95%CI: 1.07~6.01], prior use of Wuweikushen capsules (OR=5.08, 95%CI: 1.05~24.67), and the lack of compliance within the past two weeks (OR=0.27, 95%CI: 0.09~0.82) were significantly correlated with the acceptance of TCM for UC treatment (P<0.05). Among the participants, A questionnaire analysis was conducted to examine the reasons why patients were willing or unwilling to accept TCM treatment. The results showed that among the 175 patients who were willing to receive TCM treatment, the majority chose it primarily because of its fewer adverse effects. In contrast, among the 33 patients. Conclusion Gender and past medication experiences make a huge difference to the acceptance of TCM treatments among UC patients. In addition, medication compliance and the affordability of TCM are also focuses of attention in clinical practice.

Key words: Ulcerative Colitis, Wuweikushen Capsules, Price of TCM, Medication Compliance, Acceptance of TCM, Multi-variable Logistic Regression Analysis

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