Progress in Clinical and Pharmacological Research of Angong Niuhuang Pills

doi:10.19803/j.1672-8629.20240592

Abstract

Abstract: Objective To evaluate the clinical efficacy of Angong Niuhuang pills in the past three years and explore their pharmacological mechanisms in order to provide a reference for subsequent research. Methods By analyzing the latest data on clinical research, the therapeutic effects of Angong Niuhuang pills against such diseases as cerebral hemorrhage, cerebral infarction, craniocerebral injury, heatstroke, sepsis, viral encephalitis and pneumonia were summerized. Additionally, current pharmacological research was reviewed to analyze the mechanisms of action of Angong Niuhuang pills. Results The study found that Angong Niuhuang pills were highly effective in treating the aforementioned diseases. Pharmacological research suggested that they worked through multiple mechanisms, including anti-inflammation, antioxidation, anti-apoptosis, regulation of autophagy and mitochondrial dysfunction, inhibition of pyroptosis and ferroptosis, and regulation of metabolic products and gut microbiota. Conclusion This study has evaluated the clinical efficacy and pharmacological mechanism of Angong Niuhuang pills in the treatment of various diseases and confirmed their therapeutic effect and multi-target characteristics, providing data for subsequent research and clinical applications.

Key words: Angong Niuhuang Pills, Neurological Function, Inflammation, Oxidation, Apoptosis, Clinic, Pharmacology, Progress

CLC Number:

R994.11
R743

BAI Xue, CHEN Yafei, TANG Tian, LIU Zhejun, WANG Guoyu, TAN Tianyang. Progress in Clinical and Pharmacological Research of Angong Niuhuang Pills[J]. Chinese Journal of Pharmacovigilance, 2025, 22(3): 349-356.

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URL: https://zgywjj.magtechjournal.com/EN/10.19803/j.1672-8629.20240592

https://zgywjj.magtechjournal.com/EN/Y2025/V22/I3/349

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