Chinese Journal of Pharmacovigilance ›› 2025, Vol. 22 ›› Issue (3): 258-262.
DOI: 10.19803/j.1672-8629.20240910

• Orginal Article • Previous Articles     Next Articles

Traditional Chinese Medicine Used in the Treatment of Gout Complicated with Osteoarthritis

BAI Xin1, WANG Min,WANG Yuan1, BAI Jianqi1, SU Shuang3, LIU Guanghui4, GUO Xiaofei1, KANG Jiaqi1, GUO Dongqi1, ZHANG Yimeng1, WANG Hao5, ZHAO Xiaoqi4,*, ZHANG Ping1#   

  1. 1Department of Pathology, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China;
    2Personnel Department, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China;
    3Department of Pharmacy, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China;
    4Department of Ultrasound, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China;
    5Department of Academic Development, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China
  • Received:2024-11-25 Online:2025-03-15 Published:2025-03-17

Abstract: Objective To study the way in which traditional Chinese medicine is used in treating gout complicated with osteoarthritis. Methods Cases of gout complicated with osteoarthritis were retrieved from the HIS system of Wangjing Hospital of China Academy of Chinese Medical Sciences collected between January 2022 and September 2024. Information about medications was retrieved before a database was established using Microsoft Excel 2016. Statistical analysis and association rule mining were conducted on the information using the Ancient and Modern Medical Records Cloud PlatformV 2.3.7 and SPSS Modeler 18.0. Results A total of 200 cases were included, with a male preponderance and a peak incidence in the 40-49 age group. Achyranthes bidentata and Lycopodium japonicum were the most frequently used oral and external Chinese herbal medicines, respectively. Medications with warm, neutral, and cold properties as well as sweet, bitter, and pungent flavors were preferred. The meridians most frequently targeted were the liver, kidney, and spleen. Both oral and external herbs were primarily used for clearing heat, promoting diuresis, and strengthening muscles and bones. The most commonly used herbal pairs were Cortex Phellodendri-Atractylodes Rhizoma and Erythrina Bark-Lycopodium japonicum, and Tongzhi Surunjiang capsules were the most frequently used combination drug. Conclusion Classical prescriptions such as Simiao powder and Sanhuang decoction play a crucial role in the TCM treatment of gout complicated with osteoarthritis. The concurrent use of proprietary medicines in TCM treatment provides a reference for rational drug use in clinical practice.

Key words: Gout, Osteoarthritis, Traditional Chinese Medicine, Clinical Medication, Simiao Powder, Sanhuang Decoction

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