Abstract: ObjectiveTo investigate the drug resistance of 2 951 pathogens for commonly used antibiotics. MethodsAntimicrobial susceptibility testing of 2 951 isolated bacteria was carried out. ResultsOf 2 951 clinical isolates gram-positive bacteria accounted for 17.45% and gram-negative bacteria accounted for 82.55%. Sensitivity of gram-positive cocci to vancomycin and linezolid was high; gram-negative bacilli showed higher sensitivity to cefoperazone sulbactam, piperacillin-tazobactam, imipenem and meropenem. ConclusionThe drug resistance rate of Escherichia coli was higher than Klebsiella pneumoniae; Acinetobacter baumannii and Pseudomonas aeruginosa display multiple drugs resistance.

Key words: anti-bacterial agents, pathogens, gram-positive bacteria, gram-negative bacteria