Pharmaceutical care of a case with vertebral osteomyelitis of Coxiella burnetiid

doi:10.19803/j.1672-8629.20240221

Abstract

Abstract: Objective To explore the starting point where clinical pharmacists can carry out pharmaceutical care for patients with special infections by studying one case of Coxiella burnetii vertebral osteomyelitis. Methods Clinical pharmacists participated in the treatment of one case of lumbar spine infection caused by Coxiella burnetii, assisted clinicians in analyzing the patient's history and etiology, proposed medications with sensitive drugs, provided sustainable pharmaceutical care for the patient, got involved in evaluating the therapeutic effect, and kept adjusting the drug treatment plans. Results and Conclusion Clinical pharmacists assisted doctors in opting for medications and ensuring stable improvement of the patient' conditions. Clinical pharmacists can do much to ensure the safety of medications by participating in a treatment team and starting with rare site infections caused by special pathogens.

Key words: Coxiella burnetii, rickettsia Q fever, chronic Q fever, vertebral osteomyelitis, pharmaceutical care

CLC Number:

R978
R969.3

SHEN Jianghua, KONG Chao, PAN Fumin, CHU Yanqi. Pharmaceutical care of a case with vertebral osteomyelitis of Coxiella burnetiid[J]. Chinese Journal of Pharmacovigilance, 2024, 21(10): 1166-1168.

Add to citation manager EndNote|Ris|BibTeX

URL: https://zgywjj.magtechjournal.com/EN/10.19803/j.1672-8629.20240221

https://zgywjj.magtechjournal.com/EN/Y2024/V21/I10/1166

References

[1] XU Q, HAN W, CAI Y, et al.A case report of the metagenomic next-generation sequencing for timely diagnosis of a traveler with nonspecific febrile Q fever[J]. Heliyon, 2024, 10(13): e33649.
[2] FU JX, PI SN, CHEN YP.Two cases of chronic Q fever endotitis in Shenzhen[J]. Chin J Infect Dis(中华传染病杂志), 2023, 41(8): 538-539.
[3] SUN HN, REN HX, HE YC.A case of Q fever infection with Coxiella burnetii endocarditis[J]. Infect Dis Info(传染病信息), 2023, 36(1): 90-93.
[4] YANG CF, ZHU S, KANG FK.Coxiella burnetii in periprosthetic joint infection: a case and systematic review[J]. Chin J Orthop(中华骨科杂志), 2023, 43(3): 185-190.
[5] GHANEM-ZOUBI N, KARRAM T, KAGNA O, et al.Q fever vertebral osteomyelitis among adults: a case series and literature review[J]. Infect Dis Nor, 2021, 53(4): 231-240.
[6] VIRK A, MAHMOOD M, KALRA M, et al. Coxiella burnetii multilevel disk space infection, epidural abscess,vertebral osteomyelitis secondary to contiguous spread from infected abdominal aortic aneurysm or graft: report of 4 cases acquired in the US and review of the literature[J]. Open Forum Infect Dis, 2017, 4(4): ofx192.
[7] KOEHLER LM, KLOPPERT B, HAMANN HP, et al.Comprehensive literature review of the sources of infection and transmission routes of Coxiella burnetii, with particular regard to the criteria of “evidence-based medicine”[J]. Comp Immunol Microbiol Infect Dis, 2019, 64: 67-72.
[8] CHERRY CC, NICHOLS HK, BESTUL NC, et al.Acute and chronic Q fever national surveillance - United States, 2008-2017[J]. Zoonoses Public Health, 2022, 69(2): 73-82.
[9] LEAHEY PA, TAHAN SR, KASPER EM, et al. Chronic Q-fever (coxiella burnetii) causing abdominal aortic aneurysm and lumbar osteomyelitis: a case report[J]. Open Forum Infect Dis, 2016, 3(1): ofv185.
[10] DORFMAN K, ERAN A, GHANEM-ZOUBI N.Q fever vertebral osteomyelitis complicating vertebroplasty[J]. Rambam Maimonides Med J, 2021, 12(1): 10430.
[11] VAN ROEDEN SE, WEVER PC, KAMPSCHREUR LM, et al.Chronic Q fever-related complications and mortality: data from a nationwide cohort[J]. Clin Microbiol Infect, 2019, 25(11): 1390-1398.
[12] MELENOTTE C, PROTOPOPESCU C, MILLION M, et al.Clinical features and complications of coxiella burnetii infections from the french national reference center for Q fever[J]. JAMA Netw Open, 2018, 1(4): e181580.
[13] WAELBERS V, DESMET S, DE MUNTER P, et al. Vertebral osteomyelitis or infected abdominal aortic endograft? A rare case of Q fever[J]. Ann Vasc Surg, 2020, 67: 03.018
[14] SUN XX, ZHU L, CHEN W.Research progresson diagnostic techniques for Q fever[J]. China Animal Health Inspection(中国动物检疫), 2019, 36(5): 57-60.
[15] MELENOTTE C, MILLION M, RAOULT D.New insights in Coxiella burnetii infection: diagnosis and therapeutic update[J]. Expert Rev Anti Infect Ther, 2020, 18(1): 75-86.
[16] BUIJS SB, VAN ROEDEN SE, VAN WERKHOVEN CH, et al.The prognostic value of serological titres for clinical outcomes during treatment and follow-up of patients with chronic Q fever[J]. Clin Microbiol Infect 2021, 27(9): 1273-1278.
[17] BUIJS SB, WEEHUIZEN JM, OOSTERHEERT JJ, et al.Chronic Q fever vertebral osteomyelitis, an underrecognized clinical entity[J]. Infect Dis (Lond), 2021, 53(4): 241-242.