Research Progress about Anaphylactoid Reactions

Abstract

Abstract: Objective To provide literature evidences for in-depth study of anaphylactoid reactions through reviewing and analyzing the symptoms, mechanism, evaluation methods and problems. Methods The related references in recent years at home and abroad about anaphylactoid reactions were collected and summarized. Results Although the symptoms are similar with allergic reactions, the mechanism is not same. The anaphylactoid reactions can occur at first contact without prior sensitization and antibody-mediated, the aftermath is serious. Currently, the detecting indicators include histamine, IgE, and so on. The diagnosis requires a overall judgment of characteristic symptoms and biological indicators. Conclusion It's urgent to establish viable preclinical evaluation methods about anaphylactoid reactions.

Key words: anaphylactoid reactions, mechanism, evaluation methods

CLC Number:

R593.1

GAO Jian-bo. Research Progress about Anaphylactoid Reactions[J]. Chinese Journal of Pharmacovigilance, 2014, 11(6): 344-346.

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（收稿日期：编辑：范燕）