Chinese Journal of Pharmacovigilance ›› 2014, Vol. 11 ›› Issue (5): 257-260.

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Protection of Bicyclol on Liver and Kidney Injury Induced by the Combination Therapy of Cisplatin and Gemcitabine in Tumor-bearing Mice

ZHANG You-wen, WEI Huai-ling, BAO Xiu-qi, ZHANG Dan, SUN Hua*   

  1. Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • Received:2016-02-03 Revised:2016-02-03 Online:2014-05-08 Published:2016-03-02

Abstract: ObjectiveTo determine the effect of bicyclol on cisplatin plus gemcitabine induced liver and kidney injury in tumor-bearing mice. MethodsC57/BL mice implanted with Lewis lung tumors for 6 days were treated with cisplatin

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