Abstract: Objective To analyze the characteristics of adverse drug reactions (ADRs) of belladonna sulfamethoxazole and trimerhoprim tablets, so as to provide reference for public safe medication. Methods 104 cases of ADRs of belladonna sulfamethoxazole and trimerhoprim tablets collected by the Jiangxi Center for ADR Monitoring in 2017, were analyzed. Results Male patients were 1.89 times that of females, the most of patients were 15 to 44 years old. Clinical manifestations were mainly skin and its accessories damage (51.95%), digestive system damage (22.73%), and systemic damage (9.74%). Past histories of adverse drug reactions of 42 cases of patients were not inquired, 2 cases were off-label drug use, 12 cases were new ADR reports. Conclusion The pharmacy should provide consultation services, sell prescription drugs by prescriptions and prevent misuse and abuse of drugs. The clinic should pay attention to the ADRs by belladonna sulfamethoxazole and trimerhoprim tablets, and alert new ADRs such as male reproductive system damage.

Key words: belladonna sulfamethoxazole and trimerhoprim tablets, adverse drug reactions, analysis