Abstract: Objective Through analysing 59 anaphylaxis cases by Compound Danshen Injection to explore the mechanism and characteristics, provide a reference for clinical rational use of drugs. Methods By searching literature in Chinese journal full -text database from 1994 to 2013, 59 anaphylaxis literatures of Compound Danshen Injection involving 59 cases, were statistically analyzed. Results In the 59 anaphylaxis cases by Compound Danshen Injection, it had no selection to sex, and anaphylaxis often occurred in aged group. The shortest time was 2 min after administration and the longest time was 16d, and the most was found in 30 minutes after administration; the major clinical manifestations of anaphylaxis involved many systems and organs, and were complex and varied, and the cardiovascular system was the first, followed by respiratory system, gastrointestinal system, systemic damage, nervous system; all cases were found timely, made an immediate withdrawal and symptomatic treatment to get satisfactory outcome, and no cases of death were reported. Conclusion The doctors and pharmacists should pay attention to the anaphylaxis caused by Compound Danshen Injection, and the clinical monitoring should be strengthened to prevent the occurrence of adverse reactions.

Key words: Compound Danshen Injection, anaphylaxis, literature analysis