Chinese Journal of Pharmacovigilance ›› 2023, Vol. 20 ›› Issue (8): 858-865.
DOI: 10.19803/j.1672-8629.20230118
Previous Articles Next Articles
YIN Yuling1, HU Chujuan1, ZHANG Xiaomeng1,2, WANG Yu1,2, ZHANG Bing1,2,*, LIN Zhijian1,2
Received:
2023-03-01
Online:
2023-08-15
Published:
2023-08-07
CLC Number:
YIN Yuling, HU Chujuan, ZHANG Xiaomeng, WANG Yu, ZHANG Bing, LIN Zhijian. Mining and validation of anti-adriamycin cardiotoxic effect of chicory extract[J]. Chinese Journal of Pharmacovigilance, 2023, 20(8): 858-865.
[1] SMRKE A, ANDERSON PM, GULIA A, et al.Future directions in the treatment of osteosarcoma[J]. Cells, 2021, 10(1): 172. [2] SINGAL PK, ILISKOVIC N.Doxorubicin-induced cardiomyopathy[J]. N Engl J Med, 1998, 339(13): 900-905. [3] FELKER GM, THOMPSON RE, HARE JM, et al.Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy[J]. N Engl J Med, 2000, 342(15): 1077-1084. [4] LIU TS, LI W.Adverse reactions and treatment of anti-tumor drugs[J]. Chinese Journal of Pharmacovigilance(中国药物警戒), 2008, 5(6): 368-372. [5] China Society of Clinical Oncology Guidelines Working Committee. China Society of Clinical Oncology (CSCO) Guidelines for the prevention and treatment of anthracycline cardiotoxicity[M]. Beijing: People's Health Publishing House, 2020: 6-28. [6] CARDINALE D, COLOMBO A, BACCHIANI G, et al.Early detection of anthracycline cardiotoxicity and improvement with heart failure therapy[J]. Circulation, 2015, 131(22): 1981-1988. [7] YANG HF, HUANG PN, LIU ZH, et al.A preliminary study on tcm syndromes and syndrome elements of anthracyclines acute cardiotoxicity[J]. Journal of Emergency in Traditional Chinese Medicine(中国中医急症), 2020, 29(12): 2092-2096. [8] WU XF, ZUO MH, DENG LP,et al.TCM treatment and clinical experience of anthracycline-induced cardiac damage[J]. Liaoning Journal of Traditional Chinese Medicine(辽宁中医杂志), 2021, 48(4): 65-68. [9] LIN ZJ, ZHANG B, LI LY.The medication history and pharmacological research progress of chicory, a national medicine[C]. Proceedings of the 2014 International Health Service Summit Forum on Traditional Chinese Medicine, 2014: 50-55. [10] VISHWADEEP S, GHANSHYAM J, AMOL M, et al.Cichorium intybus inhibits doxorubicin - induced myocardial fibrosis in Wistar Rats Via inflammatory markers and collagen Repression[J]. European Journal of Medicinal Plants, 2021, 32(2): 51-61. [11] ELGHARABAWY RM, ALHOWAIL AH, EMARA AM, et al.The impact of chicory (Cichoriumintybus L.) on hemodynamic functions and oxidative stress in cardiac toxicity induced by lead oxide nanoparticles in male rats[J]. Biomed Pharmacother, 2021, 5(137): 111324. [12] SEDIGHI M, GHORBANZADEH V, ABASZADEH S, et al.Up-regulation of chemokine receptor type 4 expression in the ischemic reperfused heart by alcoholic extract of Cichorium intybus rescue the heart from ischemia injury in male rat[J]. Journal of Pharmacy and Pharmacology, 2021, 73(10): 1351-1360. [13] MANJU S, AIMAN A, SHRIDHAR D, et al.Cichorium intybus attenuates streptozotocin induced diabetic cardiomyopathy via inhibition of oxidative stress and inflammatory response in rats[J]. Interdisciplinary Toxicology, 2019, 12(3): 111-119. [14] EPURE A, PÂRVU AE, VLASE L, et al. Cardioprotective and nephroprotective activity of romanian chicory extract[J]. Plants, 2020, 10(1): 64. [15] Nayeemunnisa and Rani MK. Cardioprotective effect of Cichorium intybus in ageing myocardium of albino rats[J]. Current Science, 2003, 84(7): 941-943. [16] SU D, LI Y, ZHANG JJ, et al.Protective effect of chicory polysaccharide on myocardial ischemia-reperfusion injury in streptomycin induced diabetes rats[J]. Heilongjiang Medicine Journal(黑龙江医药), 2011, 24(1): 112-113. [17] LI Y, LIU XS, YANG X, et al.The protective effect of chicory polysaccharides on diabetic-resulted myocardial ischemia-reperfusion injury in rats[J].Chinese Journal of Gerontology(中国老年学杂志), 2013, 33(2): 330-331. [18] LIU JH, WU H, XING QW, et al.Effect of cichoric acid on hematology indicators and myocardial in a hypoxic environment in SD rats[J]. Feed Research(饲料研究), 2021, 44(23): 73-77. [19] LI YL.The study of protective effects chicoric acid on myocardial injury in rats with sepsis[D]. Nanchang: Nanchang University, 2019. [20] LI YL, YAO P, QI H, et al.Effects of cichoric acid on oxidative stress and its relationship with Nrf2 signal pathway in septic rats with myocardial injury[J]. Chinese Journal of Anesthesiology(中华麻醉学杂志), 2021, 41(4): 491-495. [21] LIU JH.Study of Echinacea purpurea extract cichoric acid on hypoxic adaptability of SD rats[D]. Xining: Qinghai University, 2022. [22] YUEERGULI Y, ASIYA H, YIN TT.Effect of chicoric acid on myocardial ischemia reperfusion injury in mice[J]. Journal of Medical Molecular Biology(医学分子生物学杂志), 2021, 18(4): 298-303. [23] CHEN MP, WANG YX, YAO RM, et al.Mechanisms of Qingkailing soft capsules against coronavirus pneumonia based on network pharmacology and experimental verification[J].Chinese Journal of Pharmacovigilance(中国药物警戒), 2023, 20(3): 253-257. [24] ZHANG ZS, LU YL, GAO YF, et al.Research progress of bitter substances in [25] FAN H, CHEN J, LIANG QY,et al.Advance in studies on chemical constituents of Cichorii Herba and their pharmacological effects[J]. Chinese Traditional and Herbal Drugs(中草药), 2016, 47(4): 680-688. [26] ZHU CS, LIN ZJ, ZHANG B, et al.Qualitative and quantitative analysis of chicory root by LC/MS and HPLC[J]. Journal of Beijing University of Traditional Chinese Medicine(北京中医药大学学报), 2016, 39(3): 247-251. [27] LUO Y, LIU S, FANG LY, et al.Contents determination of effective components in cichorium intybus by HPLC[J]. West China Journal of Pharmaceutical Sciences(华西药学杂志), 2007, 6: 671-672. [28] ZHOU J.Comprehensive evaluation of the quality of aboveground medicinal materials of chicory[D]. Beijing: Beijing University of Chinese Medicine, 2014. [29] PEI TX, XU CQ, LI B, et al.Protective effect of quercetin against adriamycin-induced cardiotoxicity and its mechanism in mice[J]. Acta Pharmaceutica Sinica(药学学报), 2007, 42(10): 1029-1033. [30] SHI YY, YANG R, ZHANG Y, et al.Research on the mechanism of luteolin against H9c2 cardiomyocyte injury through MIEF1[J]. Natural Product Research and Development, 2020, 32(5): 820-825. [31] CHOI EH, CHANG HJ, CHO JY, et al.Cytoprotective effect of anthocyanins against doxorubicin-induced toxicity in H9c2 cardiomyocytes in relation to their antioxidant activities[J]. Food Chem Toxicol,2007,45(10):1873-1881. [32] DU XF, GAO J, ZHANG H.Kaempferol enhances the anticancer effect of doxorubicin in breast cancer models[J]. Chinese Journal of Anatomy(解剖学杂志), 2022, 45(2): 135-141,207. [33] HE P, WANG YJ.Progress in the pathogenesis and diagnosis and treatment of anthracycline related cardiotoxicity[J]. Modern Medicine and Health Research Electronic Journal(现代医学与健康研究电子杂志), 2020, 4(8): 114-117. [34] ZHANG L, ZHAO H, ZHANG X, et al.Nobiletin protects against cerebral ischemia via activating the p-Akt, p-CREB, BDNF and Bcl-2 pathway and ameliorating BBB permeability in rat[J]. Brain Res Bull, 2013, 7(96): 45-53. [35] CHE RQ, CUI XJ, MA CM.Pioglitazone ameliorates doxorubicin-induced cardiotoxicity through PI3K/AKT pathway[J].Medical Journal of Wuhan University(武汉大学学报医学版), 2021, 42(3): 402-406. [36] LYU J, YANG SX, HAU XF, et al.Sinigrin protects against doxorubicin-induced cardiotoxicity via the p38/JNK MAPK pathway[J].International Journal of Cardiovascular Disease, 2020, 47(1): 48-51. [37] ZHANG FH, HAO JF, ZHANG ZY, et al.Impacts of cichoric acid on neuronal apoptosis and inflammatory response in ischemic stroke rats by regulating p38 MAPK/ NF- [38] ZHU D, WANG Y, DU Q, et al.Cichoric acid reverses insulin resistance and suppresses inflammatory Responses in the Glucosamine-Induced HepG2 cells[J]. J Agric Food Chem, 2015, 63(51):10903-10913. [39] ICHIKAWA Y, GHANEFAR M, BAYEVA M, et al.Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation[J].J Clin Invest, 2014, 124(2):617-630. [40] ARUNACHALAM S, NAGOORMEERAN M, AZIMULLAH S, et al.Nerolidolattenuates oxidative stress, inflammation,and apoptosis by modulating Nrf2/MAPK signaling pathways in doxorubicin-induced acute cardiotoxicity in rats[J]. Antioxidants (Basel, Switzerland), 2021, 10(6): 984. [41] LI J, WANG PY, LONG NA, et al.p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities[J]. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116(39): 19626-19634. [42] LISA FD, GIORGIO M, FERDINANDY P, et al New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases[J]. Br J Pharmacol, 2017, 174(12): 1690-1703. [43] ZHANG J, SUN Z, LIN N, et al.Fucoidan from fucus vesiculosus attenuates doxorubicin-induced acute cardiotoxicity by regulating JAK2/STAT3-mediated apoptosis and autophagy[J]. Biomed Pharmacother, 2020, 10(130): 110534. [44] LI B, ZHAO X, ZHANG L, et al.Emodin interferes with AKT1-mediated dna damage and decreases resistance of breast cancer cells to doxorubicin[J] . Frontiers in Oncology, 2021, 2(11): 588533. [45] QIN AQ, LIANG JY, LI XF, et al.Acute cardiotoxicity induced by doxorubicin in mice of different strains: a comparative study[J]. Pharmacology and Clinics of Chinese Materia Medica(中药药理与临床), 2021, 37(6): 161-166. [46] WANG XL, CHEN YN, HUANG HQ, et al.Study on astragaloside IV alleviating the cardiotoxicity caused by doxorubicin by inhibiting MerTK[J].Journal of Bengbu Medical College(蚌埠医学院学报), 2021, 46(6): 717-721. [47] HAILIMAN YLH, WULIYA YM, WANG XW.Stereolal study of protective effect of glycosides of cistanche on mitochondria of cardiac muscle against adriamycin[J].Journal of Xinjiang Medical University(新疆医科大学学报), 2004(2): 128-130. [48] XU BP.Study on the effect and mechanism of buguzhiding in preventing adr myocardial injury[D]. Xi'an: Northwest University, 2021. [49] CALEMA TU, YAP SC, GELEIJNES ML, et al.Early detection of leftventricular dysfunction by doppler tissue imaging and N-teminal-pro-B-type natriuretic peptide in patients with synptomatic serene aor-tic stenosis[J].J Am Soc Echocardiogr, 2008, 21(3): 257-261. [50] LIN LY, LIN YS.The value of serum prealbumin combined with N-terminal B-type natriuretic peptide precursor in evaluating the severity and prognosis of chronic heart failure[J]. Chronic Pathematology Journal(慢性病学杂志), 2021, 22(3): 446-448. |
[1] | WANG Xinwei, PENG Yifeng, SUN Jing, JI Zuen, BAO Lei, LUO Henglei, GENG Zihan, ZHANG Hujuan, LI Shuran, ZHANG Jingsheng, GUO Shanshan, CUI Xiaolan, ZHAO Ronghua. Effect of Yiye Anti-Influenza Capsules on Pneumonia Induced by Human Coronavirus 229E Infection in Mice [J]. Chinese Journal of Pharmacovigilance, 2025, 22(8): 851-855. |
[2] | XIE Rui, SUN Qiyue, LI Yanying, ZHANG Jingsheng, ZHAO Ronghua, GUO Shanshan, GENG Zihan, BAO Lei, GAO Shuangrong, CUI Xiaolan, XIE Dan, SUN Jing. Impacts of Shuangshenling Granules on a Cadmium-Induced Chronic Renal Failure Model of Mice [J]. Chinese Journal of Pharmacovigilance, 2025, 22(8): 856-862. |
[3] | REN Yuke, QU Zhe, LAI Zixuan, ZHANG Di, ZHAO Yongtian, YANG Yanwei, LI Shuangxing, HUO Guitao, ZHOU Xiaobing, LIN Zhi, GENG Xingchao. Pharmacodynamic Evaluation of CAR-T Cell Products Based on Deep Learning Convolutional Neural Network Recognition [J]. Chinese Journal of Pharmacovigilance, 2025, 22(7): 742-748. |
[4] | LIN Lin, YANG Tingyu, GAO Rong, MA Zengchun, SHEN Xin, GAO Yue. Effects of Sinomenine in Brassica rapa L. against Hypoxic Pulmonary Vascular Injury [J]. Chinese Journal of Pharmacovigilance, 2025, 22(6): 608-613. |
[5] | HU Haipeng, YAO Weijie, FENG Xin. Effects of Yangxue Antai Prescription on Placental Ferroptosis in Recurrent Spontaneous Abortion Mice [J]. Chinese Journal of Pharmacovigilance, 2025, 22(6): 621-626. |
[6] | ZHAO Ronghua, ZHU Chunxu, SUN Jing, BAO Lei, WANG Xinwei, GENG Zihan, ZHANG Jingsheng, GUO Shanshan, LI Shuran, WANG Daohan, CUI Xiaolan. Mechanisms of Sanhan Huashi Granules on a Respiratory Syncytial Virus and Influenza Virus and Respiratory Syncytial Virus Induced Pneumonia Model in Mice [J]. Chinese Journal of Pharmacovigilance, 2025, 22(5): 488-494. |
[7] | CHEN Runji, SUN Xiaorui, HUANG Xin, JIANG Zhenzhou, ZHANG Luyong, WANG Xinzhi, DING Jian. Dynamic Immunophenotyping of NK Cells in Triptolide-Induced Hepatotoxicity [J]. Chinese Journal of Pharmacovigilance, 2025, 22(5): 517-522. |
[8] | BU Zixuan, XUE Mengwei, TIAN Jiawei, KE Kaile, WANG Ziying, LI Xiao, LU Tiangong. Interventions of Guizhi Fuling Pills in Properties of Ovarian Cancer Stem Cells [J]. Chinese Journal of Pharmacovigilance, 2025, 22(3): 263-270. |
[9] | TANG Qianhui, ZHU Ying, ZHANG Haoran, ZHANG Luyong, JIANG Zhenzhou. Roles of Hepatocellular NF-κB Signaling Pathway in Triptolide-Induced Indirect Liver Injury [J]. Chinese Journal of Pharmacovigilance, 2025, 22(2): 128-138. |
[10] | LIANG Xiaojing, CHEN Xin, NONG Cheng, LI Liang, DING Jian, ZHANG Luyong, JIANG Zhenzhou, WANG Xinzhi. Screening of in vitro Stimulation Methods for iNKT Cells and Conditions for in vitro Activation of iNKT Cells by Triptolide [J]. Chinese Journal of Pharmacovigilance, 2025, 22(2): 147-154. |
[11] | GAN Yena, HAN Sheng, YUAN Yi, XUE Lijuan, HUANG Haowen, LI Huanxin, ZHANG Xinci, KUI Siyi, MENG Bofei, LI Qifei, ANARGUL Tudi, LIU Zhifeng, QIN Lingling, LI Duoduo. Possible Molecular Mechanisms of Dachengqi Decoction for Improving Subjective Symptoms of Degenerative Lumbar Spinal Stenosis: a Network Pharmacology Study [J]. Chinese Journal of Pharmacovigilance, 2025, 22(2): 162-168. |
[12] | HOU Tiantian, WANG Xudong, YANG Ping, ZHOU Pengbo, QIN Chao, HUANG Ying, WANG Ailing, GENG Xingchao, ZHOU Xiaobing, LIU Defang. Biodistribution of Therapeutic DNA Vaccines in Mice [J]. Chinese Journal of Pharmacovigilance, 2025, 22(1): 58-66. |
[13] | ZHENG Haiyun, ZHANG Wen, WANG Shaonan, ZHAO Haiyu, DU Shouying. Anti-fatigue effects and mechanism of ginseng combined with caffeine in rats [J]. Chinese Journal of Pharmacovigilance, 2024, 21(8): 863-870. |
[14] | ZHANG Kaihua, LIU Dingwei, FU Changhai, SUN Xuelin, MIN Xianjun. Effects of rosastatin combined with Danggui Buxue Tang on expressions of AR and NR3C2 [J]. Chinese Journal of Pharmacovigilance, 2024, 21(8): 871-877. |
[15] | LIU Yadi, ZHANG Xiaomeng, CAI Haili, CHEN Siying, WANG Yu, ZHANG Bing. Traditional Chinese medicine for prevention and treatment of adriamycin cardiotoxicity and an empirical study of evidence elements [J]. Chinese Journal of Pharmacovigilance, 2024, 21(7): 759-764. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||