Abstract: Objective To observe the effects of clinical pharmacy service mode in patients with liver dysfunction, and to explore the pharmaceutical service method.Methods 315 cases of patients with liver injury in our hospital from June 2016 to May 2017 were included for this study. According to the time of admission,158 patients from June to November in 2016 were assigned to the control group, 157 patients from December 2016 to May 2017 were assigned to the observation group. Patients in the observation group received standardized clinical pharmacy service according to Child-Turcotte-Pugh (CTP) score, and the control group only received conventional pharmacy services. The indicators of pharmacodynamics, economics, rational use of drugs and pharmaceutical service effects were compared between the two groups, and the experience of clinical pharmacy service mode was summarized.Results The total efficacy of the observation group was 98.09%, which was higher than 89.87% of the control group. The hospitalization duration, the total hospitalization expenses, the cost of protecting the liver drug, the total cost of medication and the total cost of medication/total hospitalization expenses ratio in the observation group were lower than those in the control group, and the difference was statistically significant (P <0.05) .The incidence rate of ADR of control group was 13.92%, which was higher than 6.37% of the observation group. The pharmacy service awareness, compliance and satisfaction of observation group were higher than the control group, the difference was statistically significant (P <0.05).Conclusion For patients with liver function damage, the standardization of clinical pharmacy service mode can improve the treatment effects, reduce the cost of treatment, ensure the rational use of drugs and improve the effects of pharmaceutical care, which is worthy of optimization and promotion.

Key words: liver function damage, pharmaceutical service mode, rational drug use, clinical pharmacist