Chinese Journal of Pharmacovigilance ›› 2025, Vol. 22 ›› Issue (2): 211-216.
DOI: 10.19803/j.1672-8629.20240456

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Usage of Nerve-Calming Chinese Herbal Patent Medicines in a Mental Health Center

ZHOU Kun1,2, MA Liang1,2,*, LI Zhaofeng1,2, CAO Bing1,2, GU Hongwei1,2, LIU Qian1,2   

  1. 1Department of Pharmacy, Wuhan Mental Health Center, Wuhan Hubei 430012, China;
    2Department of Pharmacy, Wuhan Hospital for Psychotherapy, Wuhan Hubei 430012, China
  • Received:2024-07-02 Online:2025-02-17 Published:2025-02-17

Abstract: Objective To investigate the usage of Chinese herbal patent medicines for calming nerves in a mental health center and to provide references for rational use of related drugs. Methods The YI-Yao Rational Drug Use Software System was used to review the prescriptions for nerve-calming Chinese herbal patent medicines from the Hospital Information System (HIS). The rationality of drug use was evaluated in terms of the days of drug use, defined daily dose (DDDs), defined daily cost (DDC) and drug utilization index (DUI). Results The top five drugs in terms of DDDs between 2018 and 2023 were Tian-meng oral liquid, Shu-gan-Jie-yu capsules, Jie-yu pills, Jian-nao capsules and Shu-mian capsules, and DUI ranged from 0.30 to 0.99. A total of 6657 improper prescriptions were screened out of 123 989 prescriptions for Chinese herbal patent medicines, so the rate of substandard prescriptions was 5.37% involving prescriptions for wrong indications (13.70%), inappropriate usage and dosage (12.36%), and inappropriate selection of drugs (2.60%). Conclusion From 2018 to 2023, the total usage and varieties of Chinese herbal patent medicines increased stably. Despite the low incidence rate of irrational use of these drugs, clinicians need to use some varieties with caution.

Key words: Chinese Herbal Patent Medicine for Calming Nerves, Defined Daily Dose (DDDs), Defined Daily Cost (DDC), Drug Utilization Index (DUI), Medication Analysis, Rational Drug Use, Mental Health Center

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