Abstract: Objective To standardize the prescription review and dispensing process of outpatient anesthetics based on the clinical rational drug use management system and hospital information system. Methods The FOCUS-PDCA method was used to identify problems, analyze the causes, formulate and implement interventions. The management system for clinical rational drug use was used to set up detailed audit rules for the indications, usage and dosage and courses of treatment. Pharmacists established medical records of outpatients with cancer pain via the electronic medical record system in the hospital information system (HIS). They also adjusted prescriptions after finding out whether an outpatient was hospitalized and when previous drugs were dispensed with. Results According to drug instructions and related laws and regulations, detailed audit rules were formulated for 8 categories of narcotic drugs and class I psychotropic drugs and for 7 categories of class II psychotropic drugs. Electronic medical records of outpatients were established for cancer patients. The refund rate of outpatient prescriptions for narcotic drugs and class I psychotropic drugs decreased from 11.41% to 2.32%, and the rate of standard use of class II psychotropic drugs increased from 86.81% to 97.83%. Conclusion The whole process management of narcotic drugs and psychotropic drugs for outpatients can improve the rate of standard prescriptions, and ensure the rationality and safety of patients' medication.

Key words: narcotic drugs, psychotropic drugs, management system for clinical rational drug use, hospital information system, PDCA, rate of rational prescriptions