Literature Analysis of 101 Cases of Adverse Reactions Induced by Huoxiangzhengqi Liquid

Abstract

Abstract: Objective Through investigating the characteristics and mechanism of adverse drug reactions (ADR) induced by Huoxiangzhengqi liquid, to find its risk factors and provide technical support for safe and rational use of drugs in clinic. Methods The keywords “Huoxiangzhengqi liquid”, “adverse reaction”, “side effect” and “induced” were used to search and retrieve articles in the CNKI databaseto extract and analyze literature data about Huoxiangzhengqi liquid. Results 33 references which met the inclusion and exclusion criteria including 101 cases. The ADRs mainly occur in the middle and young individuals. The primary diseases were acute gastroenteritis. 85.15% of ADRs happened in 1 h after administration. Systems and organs mainly involved in ADRs were systematic disorders, neurological and psychiatric system disorders, cardiovascular system disorders, skin and its appendages disorders, etc. The systematic disorders were the most common reported ADRs, including red hot, anaphylactic shock, double sulfur shimron reaction, anaphylactoid reaction, etc. Conclusion It is important to pay attention to the ADRs caused by Huoxiangzhengqi liquid, strengthen clinical rational use of drugs, and improve the medical instructions.

Key words: Huoxiangzhengqi liquid, adverse drug reactions, literature review

CLC Number:

R994.11

LIU Song-song XIE Yi-ming. Literature Analysis of 101 Cases of Adverse Reactions Induced by Huoxiangzhengqi Liquid[J]. Chinese Journal of Pharmacovigilance, 2017, 14(5): 317-320.

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