Abstract: Objective To explore the modes and ideas of clinical pharmacists' participation in clinical drug treatment. Methods Clinical pharmacist participated in the whole treatment process of hemorrhage induced by oral warfarin patient with mechanical heart valve prostheses, and provided recommendations on rational drug use for doctors, gave pharmaceutical care and drug knowledge education on patient. Results Clinical pharmacist made treatment program more reasonable and reduced the incidence of adverse drug reactions. Conclusion Clinical pharmacist can further promote the safe, effective and reasonable drug use in clinic by providing clinical pharmacy services.

Key words: warfarin, drug interactions, clinical pharmacist, rational drug use