Abstract: Objective To develop a method for the determination of a total of 20 elements such as plumbum (Pb), copper (Cu), arsenic (As), cadmium (Cd), mercury (Hg), manganese (Mn), nickel (Ni), thalliu (Tl) in Lonicera japonica and Lonicera hypoglauca. Methods The samples were digested by microwave-assisted method and then chose appropriate determination parameters of ICP-MS, using Ge and In as the internal standard. Results All the correlation coefficients exceeded 0.9993, showing good linearities over the concentration range. The lower limit of detection of the assay ranged from 0.004 to 0.071 μg·L-1. The method exhibited good precision and accuracy, while the recoveries ranged from 80% to 100%. Conclusion The method is simple, accurate and highly sensitive, successfully applied to rapid monitoring the multi-elements in Lonicera japonica and Lonicera hypoglauca for the quality control and identification.

Key words: Lonicera japonica, Lonicera hypoglauca, inductively coupled plasma mass spectrometer (ICP-MS), microwaves digest, element analysis