Analysis of Uncertainty of Measurement in the Determination of Curcumin in Tiaozhi Granules

Abstract

Abstract: ObjectiveTo analyze the measurement uncertainty in determination of curcumin in Tiaozhi granules. MethodsAccording to the measurement uncertainty principle and National Measurement Technology Criterion, mathematic model of HPLC was established to analyze the effects of many uncertain factors on measurement results. Combined standard uncertainty and expanded standard uncertainty were calculated. ResultsThe expanded uncertainty was 8mg per bag and the results of determination could be expressed as(97.7±8.0)mg per bag(k=2). ConclusionThe established analytical method is applicable to the uncertainty analysis in the content determination of Tiaozhi granules.

Key words: uncertainty, HPLC, Tiaozhi granules, curcumin

CLC Number:

R917

ZANG Ya-ju. Analysis of Uncertainty of Measurement in the Determination of Curcumin in Tiaozhi Granules[J]. Chinese Journal of Pharmacovigilance, 2014, 11(4): 206-209.

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Analysis of Uncertainty of Measurement in the Determination of Curcumin in Tiaozhi Granules

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