Abstract: Objective To search the factors, characteristics and rules that lead to adverse drug reaction/event(ADR/ADE) and provide references of the rational use of drugs by analyzing 1568 Cases of ADR/ADE in Hainan Province in 2010. Methods 1568 Cases of ADR/ADE were comprehensively analyzed in respect of the patients' sex, age, drug categories, clinical manifestations and route of administration, etc. by means of Excel. Results Most patients who had ADR/ADE were children(≤10years). Most cases of ADR/ADE were caused by anti-infective drugs. The intravenous medication was the main route of administration result in ADR/ADE. Lesions of the skin and its appendages were the main manifestations of ADR/ADE. Conclusion It is to improve rational use of drugs in clinic that ADR monitoring and propaganda should be strengthened, harmful habit of drug use should change, and anti-infective drugs and intravenous medication should be used rationally.

Key words: adverse drug reaction/event(ADR/ADE), analysis