Abstract: Objective To investigate the usage of prophylactic Antibacterials for perioperative nodular goiter patients in our hospital. Methods 232 nodular goiter cases were randomly selected from general surgery department during June-December 2010. Evaluation was carried out to investigate the preventive usage of antibacterials during perioperation, according to the Guiding Principles of Clinical Application of Antibacterials. Results Prophylactic antibacterials were used for all the 232 cases(100.0%), among which aminoglycosidesand penicillins were mostly used. Conclusion Admi-nistration and inspection should be enhanced for the perioperative antibacterials use, in order to improve clinical rational drug use.

Key words: nodular goiter, perioperative, antibacterials, rational use of drug