Abstract: Objective To statistically analyze the improper prescriptions detected by the pharmacy intravenous admixture service of the Second Hospital of Hebei Medical University between 2017 and 2018 so as to provide reference for the rationality, safety and effectiveness of clinical medication. Methods The data on 667705 medical prescriptions were classified and collected from the pharmacy intravenous admixture service of The Second Hospital of Hebei Medical University from 2017 to 2018. To sum up, sort out and analyze the irrational medical advice. Results There were 16 180 irrational medical advices, accounting for 2.42% of the total medical advices. The irrational factors included wrong Format of Doctor's Order, improper selection of solvent varieties, inappropriate dosage of drugs, TPN inappropriate formula, improper dosage of solvent, nappropriate compatibility of drugs, improper frequency of drug use, incompatibility of drugs in a prescription, repeated medication, incorrect use of drugs. Conclusion Irrational medical prescriptions can be found and intervened in time by examination of prescriptions of pharmacists, which not only can reduce the incidence of intravenous administration clinical adverse reactions, but also ensure the rationality and safety of patient's medication, promoting the specialization of patient drug use.

Key words: pharmacy intravenous admixture service, irrational medical prescriptions, rational use of drugs.