Chinese Journal of Pharmacovigilance ›› 2020, Vol. 17 ›› Issue (10): 692-696.
DOI: 10.19803/j.1672-8629.2020.10.09

Previous Articles     Next Articles

High-risk Medications in Elderly Patients in Our Hospital Based on List of High-risk Perioperative Medications

DONG Na1,2, HE Dan1,2, WU Xiaoyan1, ZHANG Haixia1,*   

  1. 1Department of Pharmacy, Nanjing Drum Tower Hospital Affiliated to Medical School, Nanjing University, Nanjing Jiangsu 210008, China;
    2School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing Jiangsu 210008, China
  • Received:2019-12-10 Revised:2020-10-14 Online:2020-10-15 Published:2020-10-13

Abstract: Objective To evaluate high-risk medications in elderly patients in our hospital based on the list of high-risk perioperative medications in order to provide more evidence for rational medications in perioperative elderly patients. Methods A total of 230 elderly patients during the perioperative period were selected from January 2018 to December 2018. The list of high-risk perioperative medications for the elderly released in 2019 was used as the criteria to evaluate the high-risk medications detected. Results In the 230 patients, 279 medications were detected, 36.52% (84/230) of whom received high-risk medications during the perioperative period, and 29.13% (67/230) used two or more types of high-risk drugs. A total of 37 types of drugs were detected, among which dexmedetomidine, diazepam and NSAID were more frequently used, accounting for 20.43%, 14.35% and 11.30% respectively. A total of 3 patients developed adverse reactions after perioperative administration. Conclusion There are potential drug risks to perioperative elderly patients in our hospital, so we should strengthen the regulation of perioperative medications in elderly patients and improve the quality of medications.

Key words: perioperative period, list of high-risk medications, elderly surgical petients

CLC Number: