Abstract: Objective To explore the general pattern and characteristics of adverse drug reactions(ADR) induced by Chuanhuning injection so as to provide references for clinical rational drug use. Methods ADR cases induced by Chuanhuning injection that retrieved from domestic medical journals during 1998~2010 were analyzed statistically. Results ADR of Chuanhuning injection were independent of patient's sex, and mostly occurred in the <10 group. They usually occurred in the first 30 minutes after taking the drug. ADR could involve in multiple organs and systems, and clinical manifestations were various, mainly were allergic reaction and thrombocytopenia,symptomatic treatment,prognosis much good. Conclusion Doctors and pharmacists should know the pattern and characteristics of ADR, and the use of Chuanhuning injection should be under strict monitoring to reduce the occurrence of serious ADR.

Key words: Chuanhuning injection, adverse drug reaction, literature, analysis