Research Progress of Epimedium in the Treatment of Male Infertility

doi:10.19803/j.1672-8629.20240638

Abstract

Abstract: Objective To assess the potential of Epimedium and its active components in the treatment of male infertility and to explore their prospects in traditional Chinese medicine therapy. Methods A systematic literature review was conducted to analyze the significant effects of Epimedium and its main active components on improving spermatogenesis, protecting the testicular microenvironment, regulating sex hormone levels, combating oxidative stress, and alleviating sexual dysfunction. Results Epimedium demonstrated the potential to protect germ cells by modulating key signaling pathways and improving apoptosis, and it also showed positive effects in improving sexual dysfunction. Conclusion The active components of Epimedium have significant potential in the treatment of male infertility. Future research should further verify their clinical efficacy to promote their application in the field of male reproductive health.

Key words: Male Infertility, Epimedium, Active Ingredients, Mechanism, Reproductive, Spermogenesis, Antioxidant Stress

CLC Number:

R917

TANG Tian, TAN Tianyang, LIU Zhejun, BAI Xue. Research Progress of Epimedium in the Treatment of Male Infertility[J]. Chinese Journal of Pharmacovigilance, 2024, 21(11): 1238-1242.

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https://zgywjj.magtechjournal.com/EN/Y2024/V21/I11/1238

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