Chinese Journal of Pharmacovigilance ›› 2024, Vol. 21 ›› Issue (10): 1169-1171.
DOI: 10.19803/j.1672-8629.20240316

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One case of severe allergic reactions caused by oxytocin injection

JU Kanglu, CHANG Ying, LIU Zhenguo*   

  1. Department of Pharmacy, Northwest Women's and Children's Hospital, Xi'an Shaanxi 710061, China
  • Received:2023-05-10 Online:2024-10-15 Published:2024-10-14

Abstract: Objective To analyze severe allergic reactions caused by oxytocin injection so as to provide references for safe and rational drug use. Methods One rare case of severe allergic reactions in a patient with missed abortion was reported, who had manifested critical symptoms after two minutes of intravenous infusion of oxytocin on the second day of continuous injection. Related literature was retrospectively analyzed. The causes and preventive measures were studied. Results The severe allergic reactions were likely related to oxytocin injection, and such cases were very rare. The symptoms were relieved after effective anti-allergic treatment. Conclusion Clinicians need to prevent severe allergic reactions caused by oxytocin injection, and early detection and treatment are crucial.

Key words: oxytocin, injection, severe anaphylactic reaction, adverse drug reaction

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