One case of anaphylactic shock caused by pamidronate disodium glucose injection

doi:10.19803/j.1672-8629.20240106

Abstract

Abstract: Objective To investigate the characteristics of anaphylactic shock triggered by pamidronate disodium in order to provide data for the prevention and treatment of adverse reactions and ensure safe medications. Methods One case of anaphylactic shock induced by pamidronate disodium was reported, with the correlations assessed using the evaluation method recommended by the National Adverse Drug Reaction Monitoring Center. Additionally, literature on the common adverse reactions and pathogenesis related to pamidronate disodium was reviewed to explore the potential causes and preventive strategies. Results The patient's clinical conditions and the timing of drug administration strongly suggested that pamidronate disodium was the likely cause of anaphylactic shock,so immediate and effective treatment was offered to alleviate the symptoms. Conclusion Clinicians who prescribe pamidronate disodium should be alert to the risk of anaphylaxis. It is crucial to enhance monitoring of adverse reactions and ensure the availability of emergency medications and equipment during treatment.

Key words: pamidronate disodium, injection, anaphylactic shock, severe allergy, adverse drug reaction, case report

CLC Number:

LIU Meng, FANG Ke, YAN Jiaju, LIU Meng, HE Manyun, WEI Liangbing. One case of anaphylactic shock caused by pamidronate disodium glucose injection[J]. Chinese Journal of Pharmacovigilance, 2024, 21(10): 1172-1174.

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URL: https://zgywjj.magtechjournal.com/EN/10.19803/j.1672-8629.20240106

https://zgywjj.magtechjournal.com/EN/Y2024/V21/I10/1172

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