Abstract: Objective To explore the role of clinical pharmacists in pharmaceutical care of a patient with Sjogren's syndrome complicated with pneumocystis carinii pneumonia. Methods Clinical pharmacists participated in the treatment of a patient with Sjogren's syndrome complicated with Pneumocystis carinii pneumonia. Due to the patient's history of sulfanilamide allergy, the lack of alternative drugs and high cost, the pharmacists suggested trying the sulfanilamide desensitization test. According to the usage recommended by the guidelines, the feasible steps of the sulfanilamide desensitization test were designed, and the desensitization program was carried out with the attending physician. At the same time, individualized pharmaceutical care was provided to ensure the efficacy and to prevent adverse reactions. Results Physicians took the advice of clinical pharmacists and the sulfanilamide desensitization test was a success. After 21 days of treatment, the lung abnormal lesion was absorbed basically and infection was brought under control. Conclusion Clinical pharmacists can optimize the therapy plan of patients through pharmaceutical care to promote rational drug use in clinic, improve the effectiveness and safety of clinical treatment, and reduce the health care cost for patients.

Key words: Sjogren's syndrome, pneumocystis carinii pneumonia, sulfanilamide desensitization test, pharmaceutical care