Chinese Journal of Pharmacovigilance ›› 2021, Vol. 18 ›› Issue (3): 284-288.
DOI: 10.19803/j.1672-8629.2021.03.17

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One Case of Drug Treatment and Pharmaceutical Care in Patients with HIT after Coronary Artery Bypass Grafting

ZHANG Yongna1,2, ZHANG Yanjiao3, ZHAO Li2,*, HAN Yongxin4   

  1. 1Deptartment of Pharmacy, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou Henan 450008, China;
    2Deptarment of Pharmacy, China -Japan Friendship Hospital, Beijing 100029, China;
    3Dept. of Pharmacy, The First People's Hospital of Yunnan Province, Kunming Yunnan 650032, China;
    4Department of Cordiovascular Surgery, China-Japan Friendship Hospital, Beijing 100029, China
  • Online:2021-03-15 Published:2021-04-06

Abstract: Objective To investigate the formulation and pharmaceutical care of a case of heparin- induced thrombocytopenia after coronary artery bypass grafting Methods The related literature were searched in recent years, the correlation evaluation of adverse drug reaction was carried out in combination with this case to assist clinicians to formulate individualized treatment plans, including the selection of anticoagulant drugs, the intervention of antibacterial drug use and the dose adjustment of warfarin sodium after discharge, and to give the patients the whole course of pharmaceutical care. Results The patient was discharged from hospital stably, platelet returned to normal, the international normalized ratio reached the standard, and no obvious embolism and bleeding were found during hospitalization. Conclusion Clinical pharmacists assist doctors to formulate and optimize the whole course treatment plan and pharmaceutical care to ensure the safety, effectiveness and economy of drug use.

Key words: heparin, coronary artery bypass grafting, heparin-induced thrombocytopenia, pharmacy care, adverse drug reaction

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