Chinese Journal of Pharmacovigilance ›› 2020, Vol. 17 ›› Issue (2): 106-110.
DOI: 10.19803/j.1672-8629.2020.02.08

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Pharmacists' Participation in the Treatment of a Patient with Complicated Abdominal Infection Secondary to Invasive Fungal Infection

ZHOU Ran1, CHEN Zhangzhang2*   

  1. 1Division of Life Sciences and Medicine, the First Affiliated Hospital of University of Science and Technology of China, Hefei Anhui 230001, China;
    2Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai 200032, China
  • Received:2019-02-12 Revised:2020-06-22 Online:2020-02-15 Published:2020-02-26

Abstract: Objective To investigate the role of clinical pharmacists in the medication of a patient with complicated intra-abdominal infection after gastrointestinal surgery. Methods By participating in the medication of a patient with complicated abdominal infection secondary to invasive fungal infection, clinical pharmacists were able to find the causes of acute kidney injury of the patient and adjusted the dosage of vancomycin immediately according to the result of treatment with vancomycin. Then, these clinical pharmacists suggested adjusting the therapeutic regimen after comparing the pharmacodynamics and pharmacokinetics of such antifungal agents as triazole, echinocandins and polyene in line with the latest guidelines before the clinicians took the advice. Results After seven days of treatment with this regimen, the blood culture of the patient was negative, so clinical pharmacists suggested that the patient be returned to an ordinary ward for further treatment. Conclusion Clinical pharmacists can assist clinicians in adjusting the drug regimen and improve the level of clinical medication by making full use of their knowledge of pharmacy.

Key words: complicated intra-abdominal infection, invasive fungal infection, clinical pharmacist, pharmaceutical care

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