[1] Mesias-garcia M, Guerra-hernandez E, Garcia-villanova B. Determination of furan precursors and some thermal damage markers in baby foods: ascorbic acid, dehydroascorbic acid, hydroxyme-thylfurfural and furfural[J]. J Agric Food Chem, 2010, 58(10): 6027-6032.
[2] Zirbes L, Nguyen B K, De Graaf D C, et al. Hydroxymethylfurfural: a possible emergent cause of honey bee mortality[J]. J Agric Food Chem, 2013, 61(49): 11865-11870.
[3] Wang M Y, Zhao F M, Peng H Y, et al.Investigation on the morphological protective effect of 5-hydroxymethylfurfural extracted from wine-processed Fructus corni on human L02 hepatocytes[J]. J Ethnopharmacol, 2010, 130(2): 424-428.
[4] Li W, Qu X N, Han Y, et al.Ameliorative effects of 5-hydroxymethyl-2-furfural (5-HMF) from Schisandra chinensis on alcoholic liver oxidative injury in mice[J]. Int J Mol Sci, 2015, 16(2): 2446-2457.
[5] 张建宏. 5-HMF抗氧化损伤作用及其作用机制的初步探讨[D].中国人民解放军军事医学科学院,2009.
[6] Zhao L, Chen J, SU J, et al.In vitro antioxidant and antiproliferative activities of 5-hydroxymethylfurfural[J]. J Agric Food Chem, 2013, 61(44): 10604-10611.
[7] 赵玲, 陈建平, 李琳, 等. 5-羟甲基糠醛抗氧化性及其抗细胞增殖活性的研究[J]. 现代食品科技, 2013, 29(11): 2638-2642.
[8] 梅国栋,赵玲,陈建平,等. 5-HMF抑制A375细胞增殖的信号转导通路[J]. 中国科技论文,2014,9(9):1005-1008.
[9] Cao G, Cai H, Cai B, et al.Effect of 5-hydroxymethylfurfural derived from processed Cornus officinalis on the prevention of high glucose-induced oxidative stress in human umbilical vein endothelial cells and its mechanism[J]. Food Chem, 2013, 140(1-2): 273-279.
[10] 孙文, 巢志茂, 王淳, 等. HPLC 对市售瓜蒌中5 一羟甲基糠醛的含量测定[J]. 中国试验方剂学杂志, 2012, 18(18): 73-76.
[11] Yalcin O, Cabrales P.Increased hemoglobin O2 affinity protects during acute hypoxia[J]. Am J Physiol Heart Circ Physiol, 2012, 303(3): H271-H281.
[12] He Y L, Li M M, Wu L Y, et al.Enhanced hypoxia-inducible factor (HIF)-1α stability induced by 5-hydroxymethyl-2-furfural(5-HMF) contributes to protection against hypoxia[J]. Molecular Medicine, 2015, 20(1):590-600.
[13] Guo M, HE L, Lu X.Binding mechanism of traditional Chinese medicine active component 5-hydroxymethyl-furfural and HSA or BSA[J].Acta Pharm Sin, 2012, 47(3): 385-392.
[14] 夏云, 李志明, 朱丹妮, 等. 化学生脉散复方化学动态变化与药效关系的研究生脉散复方化学的研究-生脉散复方化学的研究(Ⅰ)[J].中国中药杂志, 1998 , 23(4):230-231.
[15] Zhang J H, Di Y, Wu L Y, et al.5-HMF prevents against oxidative injury via APE/Ref-1[J]. 178Free Radic Res, 2015, 49(1): 86-94.
[16] Kubo M, Asano T, Matsuda H, et al.[Studies on Rehmanniae radix. III. The relation between changes of constituents and improvable effects on hemorheology with the processing of roots of Rehmannia glutinosa][J]. Yakugaku zasshi: Journal of the Pharmaceutical Society of Japan, 1996, 116(2): 158-68.
[17] Li M M, Wu L Y, Zhao T, et al.The protective role of 5-hydroxymethyl-2-furfural (5-HMF) against acute hypobaric hypoxia[J]. Cell Stress & Chaperones, 2011, 16(5):529-537.
[18] Ya B L, Li H F, Wang H Y, et al.5-HMF attenuates striatum oxidative damage via Nrf2/ARE signaling pathway following transient global cerebral ischemia[J]. Cell Stress & Chaperones, 2017:55-65.
[19] Zhang L N, Jin G Q, Zhang X L, et al.Effects of 5-hydroxymethyl furfural extracted from Rehmannia glutinosa Libosch on the expression of signaling molecules relevant to learning and memory among hippocampal neurons exposed to high concentration of corticosterone[J]. Chin J Integr Med, 2014, 20(11): 844-849.
[20] Liu A, Zhao X, LI H, et al.5-Hydroxymethylfurfural, an antioxidant agent from Alpinia oxyphylla Miq. improves cognitive impairment in Abeta 1-42 mouse model of Alzheimer's disease[J]. Int Immunopharmacol, 2014, 23(2): 719-725.
[21] Lee Y, Gao Q, Kim E, et al.Pretreatment with 5-hydroxymethyl-2-furaldehyde blocks scopolamine-induced learning deficit in contextual and spatial memory in male mice[J]. Pharmacology Biochemistry& Behavior, 2015, 134:57-64.
[22] Wölkart G, Schrammel A, Koyani C N,et al. Cardioprotective effects of 5-hydroxymethylfurfural mediated by inhibition of L type Ca2+ currents[J]. British Journal of Pharmacology, 2017, 174(20):3640-3653.
[23] Yamada P, Nemoto M, Shigemori H, et al.Isolation of 5-(hydroxymethyl)furfural from Lycium chinense and its inhibitory effect on the chemical mediator release by basophilic cells[J]. Planta Med, 2011, 77(5): 434-440.
[24] Kim H K, Choi Y W, Lee E N, et al.5-Hydroxymethylfurfural from Black Garlic Extract Prevents TNFα-induced Monocytic Cell Adhesion to HUVECs by Suppression of Vascular Cell Adhesion Molecule-1 Expression, Reactive Oxygen Species Generation and NF-κB Activation[J]. Phytotherapy Research Ptr, 2011, 25(7):965-974.
[25] Jiang Z Q, Ma Y X, LI M H,et al.5-Hydroxymethylfurfural protects against ER stress-induced apoptosis in GalN/TNF-α-injured L02 hepatocytes through regulating the PERK-eIF2α signaling pathway[J]. Chinese Journal of Natural Medicines, 2015, 13(12):896-905.
[26] Uubricht R J, Northup S J, Thomas J A.A review of 5-hydrox-ymethylfurfural (HMF) in parenteral solutions[J]. Fundamental and applied toxicology: official journal of the Society of Toxicology, 1984, 4(5): 843-853.
[27 Guo M, He L, Lu X W. Binding mechanism of traditional Chinese medicine active component 5-hydroxymethyl-furfural and HSA or BSA[J]. Acta Pharmaceutica Sinica, 2012, 47(3):385-392.
[28] Wang L, Yuan Q, Marshall G, et al.Adverse drug reactions and adverse events of 33 varieties of traditional Chinese medicine injections on National Essential medicines List (2004 edition) of China: an overview on published literatures[J].Evidence Based Medcine,2010,3(2):95-104.
[29] Ji K, Chen J, Li M, et al.Comments on serious anaphylaxis caused by nine Chinese herbal injections used to treat common colds and upper respiratory tract infections[J]. Regulatory Toxicology& Pharmacology Rtp, 2009, 55(2):134-138.
[30] Nierkens S, Aalbers M, Bol M, et al.Development of an oral exposure mouse model to predict drug-induced hypersensitivity reactions by using reporter antigens[J]. Toxicological Sciences An Official Journal of the Society of Toxicology, 2005, 83(2):273-281.
[31] Lin N, Liu T, Lin L, et al.Comparison of in vivo immunomodulatory effects of 5-hydroxymethylfurfural and 5, 5'-oxydimethylenebis (2-furfural)[J]. Regulatory Toxicology & Pharmacology, 2016, 81:500-511.
[32] Bakhiya N, Monien B, Frank H, et al.Renal organic anion transporters OAT1 and OAT3 mediate the cellular accumulation of 5-sulfooxymethylfurfural, a reactive, nephrotoxic metabolite of the Maillard product 5-hydroxymethylfurfural[J]. Biochem Pharmacol, 2009, 78(4): 414-419.
[33] Bauer-marinovic M, Taugner F, Florian S, et al. Toxicity studies with 5-hydroxymethylfurfural and its metabolite 5-sulphooxymethy-lfurfural in wild-type mice and transgenic mice expressing human sulphotransferases 1A1 and 1A2[J]. Arch Toxicol, 2012, 86(5): 701-711.
[34] Florian S, Bauer-marinovic M, Taugner F, et al. Study of 5-hydroxymethylfurfural and its metabolite 5-sulfooxymethylfurfural on induction of colonic aberrant crypt foci in wild-type mice and transgenic mice expressing human sulfotransferases 1A1 and 1A2[J]. Mol Nutr Food Res, 2012, 56(4): 593-600.
[35] Svendsen C, Husøy T, Glatt H, et al. 5-Hydroxymethylfurfural and 5-sulfooxymethylfurfural increase adenoma and flat ACF number in the intestine of Min/+mice[J]. Anticancer research, 2009, 29(6): 1921-1926.
[36] Abraham K, Gurtler R, Berg K, et al.Toxicology and risk assessment of 5-Hydroxymethylfurfural in food[J]. Mol Nutr Food Res, 2011, 55(5): 667-678.
[37] S urh Y-J, Tannenbaum S R. Activation of the Maillard reaction product 5-(hydroxymethyl) furfural to strong mutagens via allylic sulfonation and chlorination[J]. Chemical research in toxicology, 1994, 7(3): 313-318.
[38] Schoental R, Hard G, Gibbard S.Histopathology of renal lipomatous tumors in rats treated with the "natural" products, pyrrolizidine alkaloids and α, β-unsaturated aldehydes[J]. Journal of the National Cancer Institute, 1971, 47(5): 1037-1044.
[39] Zhu J, Chen L, Dong Y, et al.Spectroscopic and molecular modeling methods to investigate the interaction between 5-Hydroxy-methyl-2-furfural and calf thymus DNA using ethidium bromide as a probe[J]. Spectrochim Acta A Mol Biomol Spectrosc, 2014, 124(7):78-83.
[40] Severin I, Dumont C, Jondeau-cabatonA, et al. Genotoxic activities of the food contaminant 5-hydroxymethylfurfural using different in vitro bioassays[J]. Toxicol Lett, 2010, 192(2): 189-194.
[41] Nishi Y, Miyakawa Y, Kato K.Chromosome aberrations induced by pyrolysates of carbohydrates in Chinese hamster V79 cells[J]. Mutation Research Letters, 1989, 227(2): 117-123.
[42] Durling L J, Busk L, Hellman B E.Evaluation of the DNA damaging effect of the heat-induced food toxicant 5-hydroxymethylfurfural(HMF) in various cell lines with different activities of sulfotransferases[J]. Food Chem Toxicol, 2009, 47(4): 880-884.
[43] Svendsen C, Meinl W, Glatt H, et al.Intestinal carcinogenesis of two food processing contaminants, 2-amino-1-methyl6-phenyli-midazo[4,5-b] pyridine and 5-hydroxymethylfurfural, in transgenic FVB min mice expressing human sulfotransferases[J]. Mol Carcinog, 2012, 51(12): 984-992.
[44] Henderson I, Couper I, Lumsden A.Potentially irritant glucose metabolites in unused CAPD fluid[M]. Frontiers in Peritoneal Dialysis. Springer,1986: 261-264.
[45] Wieslander A, Andren A, Nilsson-thorell C, et al. Are aldehydes in heat-sterilized peritoneal dialysis fluids toxic in vitro?[J]. Peritoneal dialysis international, 1995, 15(8): 348-352.
[46] National Pharmacopoeia Commission.Pharmacopoeia of the People's Republic of China[M]. Part II.Glucose Injection: Limit of 5-Hydroxymethylfurfural. Beijing:China Medical Science Press, 2015: 1270-1271.
[47] Dunn R T, Klaassen C D.Tissue-specific expression of rat sulfotransferase messenger RNAs[J]. Drug Metabolism and Disposition, 1998, 26(6): 598-604.
[48] Teubner W, Meinl W, Florian S, et al.Identification and localization of soluble sulfotransferases in the human gastrointestinal tract[J]. Biochemical Journal, 2007, 404(2): 207-215.
[49] 贺浪冲. 2D/CMC分析仪研制及其在中药注射剂过敏物筛选中的应用[C]//中国药学大会暨中国药师周报告集. 2015.
[50] 韩省力, 张涛, 贺浪冲. 细胞膜色谱用于中药注射液致敏组分筛选的研究及应用[C]//全国色谱学术报告会及仪器展览会. 2015.
[51] Ros-polski V, Popović V Koutchma T. Effect of ultraviolet-C light treatment on Hydroxymethylfurfural (5-HMF) content in high fructose corn syrup (HFCS) and model syrups[J]. Journal of Food Engineering, 2016, 179:78-87. |