Abstract: Objective To investigate the characteristics and general pattern of the adverse drug reactions (ADR) occurred in a psychiatric hospital. Methods A total of 365 ADR cases collected in Beijing Huilongguan Hospital from 2010 to 2014 were analyzed statistically in terms of patients' age,sex,drug category,causality assessment, degree evaluation, drug combination, ADR involved organs or systems and clinical manifestations,ect. Results Among 365 cases of ADR reports, most patients were form 21 to 30 years old, accounting for 111 cases (30.41%). ADR caused by antipsychotics in 14 varieties were in the first place, accounting for 345 cases (74.35%). Systems or organs involved in ADR cases were most frequently reported as central and peripheral nervous system disorders (30.25%) and gastrointestinal system disorders(18.86%). Conclusion Attention should be paid to the ADR monitoring and reporting work, especially serious adverse reaction reporting and monitoring for the rational use of drugs,strengthen the ADR analysis,evaluation, timely intervention and persuation. It is better for patients to use drugs according to themselves so as to reduce the ADR and ensure safe drug use.

Key words: adverse drug reactions, psychiatric hospital, retrospective analysis, rational drug use