Chinese Journal of Pharmacovigilance ›› 2011, Vol. 8 ›› Issue (5): 294-298.

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Common Signal Detection Methods of Adverse Drug Reaction

REN Jing-tian1,2, WANG Sheng-feng1, HOU Yong-fang2, DU Xiao-xi2, LI Li-ming1   

  1. 1. Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China;
    2. Center for Drug Reevaluation,SFDA, Beijing 100045, China
  • Received:2015-08-27 Revised:2015-08-27 Online:2011-05-10 Published:2015-08-27

Abstract: This paper aims to give some references for adverse drug reaction(ADR) signal detection in China, by summarizing the common used signal detection Methods and rationale, such as the Reporting Odd Ratio, Proportional Reporting Ratio, Information Component and Gamma-Poisson Shrinker.

Key words: adverse drug reaction, signal detection, data mining

CLC Number: