Abstract: Objective To investigate the clinical feature and pharmaceutical care of inpatients with drug eruption, especially those with severe drug eruption. Methods A retrospective analysis was carried out on the clinical date on all patients(42cases) with drug eruption from July 2009 to December 2009. Results The composition of causative drugs was an-timicrobial drugs(50.00%), antipyretic analgesic(19.05%), biological products(4.76%), antigout drugs(2.38%). The com-position of clinical manifestation was rash erythematous(69.05%), maculopapular type(14.29%), urticaria type(7.14%), fixed eruption type(4.76%) and severe drug eruption. Conclusion The major involved drugs inpatients with drug eruption are antimicrobial drugs and antipyretic analgesic, while those in patients with severe types are antiepileptic drugs. It is necessary for medical staff to know the drug history of inpatients, stop using questionable allergize drugs promptly, receive pharmaceutical care provided by clinical pharmacists.

Key words: drug eruption, erythra, pharmaceutical care