Abstract: Objective To analyze the characteristics of ADR induced by Shenmai injection so as to promote the rational use of the drugs． Methods 56 cases of ADR relate to the Shenmai injection from January 2010 to June 2012 in Harbin were analyzed statistically from patients with normal circumstances, adverse reaction time, clinical manifestation, drug use and other aspects. Results Most of the patients taking the drug were old people whose average age was 53.28. The cases occurred within 30 minutes account for 83.93 % of the total. Most of the reports(n=28) involved both of the skin system and its appendages, accounting for 36.36%. All of these cases were single medication using. Conclusion The ADR of Shenmai injection was related to the pharmaceutical factors. What's more, age distribution accorded with the indications for the crowd of the drug. Enterprises, doctors and pharmacists should pay more attention to the ADR of Shenmai injection. The process of drug use should be monitored to reduce the incidence of ADR.

Key words: Shenmai injection, adverse drug reactions