Chinese Journal of Pharmacovigilance ›› 2010, Vol. 7 ›› Issue (7): 439-441.

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Analysis of 212 Adverse Drug Reaction/Event Reports of Fluoroquinolone

DING Qing-ming1,2, XU Xiao-hua2, LU Jin2   

  1. 1Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100073, China;
    2Department of Pharmacy, China-Japan Friendship Hospital, Beijing 100029, China
  • Received:2016-02-22 Revised:2016-02-22 Online:2010-07-08 Published:2016-02-22

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Abstract: Objective To analyze relevant factors of the adverse drug reaction/event(ADR/ADE) induced by Fluoro-quinolons. Methods 212 ADR/ADE reports collected by Fluoroquinolones in China-Japan Friendship Hospital from 2004 to 2009 have been analyzed retrospectively. Results ADRs/ADEs induced by injection were most. The female had higher probability of occurrence. The clinical manifestation of ADR/ADE mainly involved system damage, skin and appendages damage, and digestive system damage. Most ADR/ADE cases happened in one day after medication. Conclusion The patients should be intensively warded after the first medication. It's important to diagnose correctly and disposal in time to the new ADR/ADE.

Key words: fluoroquinolone, adverse drug reaction/event(ADR/ADE), analysis

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