Abstract: Objective Over the past five years 471 patients drug-induced adverse drug reaction of gastrointestinal tract in our hospital were retrospectively analyzed to provide reference for the clinical reasonable medication and obviating adverse drug reaction of gastrointestinal tract. Methods 471 adverse drug reaction of gastrointestinal tract cases col-lected from 2005 to 2008 in our hospital were analyzed statistically. Results 471 adverse drug reaction of gastrointestinal tract cases refered to 201 kinds of drugs. Of which anti-infective agents occupied the first place which had 218 cases(46.28%).Followed by the traditional Chinese medicine which had 88 cases(18.68%).The majority of patients(36.94%) were over 55-years-old, and 257 cases(54.57%) were given orally. Conclusion Clinic should attach great importance to the reporting and principle and enhance to the obviating and detection of adverse drug reaction of gastrointestinal tract to reduce or avoid the occurrence of it, and to use reasonably safe and effective medications.

Key words: gastrointestinal tract system, adverse drug reaction(ADR)