Abstract: Objective To provide reference for safe, effective and reasonable use of Qiliqiangxin Capsules in clinic. Methods Serum digoxin concentration was determined by chemiluminescence immune inspection technology, and the monitoring Results were subjected to statistical analysis. Results Of the total 258 cases who were treated with Qiliqiangxin Capsules, 91.09% serum digoxin concentrations were below 2 ng?mL-1, 8.91% were above 2 ng?mL-1, with 7 cases(2.71%) having symptoms of poisoning. The concentration in the group above the age of 60 years old was higher than that in the group under 60 years old (P＜0.05). Sex had no perfect statistical mean(P＞0.05). Conclusion To ensure clinical efficacy and reduce incidence of Qiliqiangxin Capsules, it's important to monitor the serum digoxin concentration.

Key words: Qiliqiangxin capsules, digitalis overdose, serum digoxin concentration