Abstract: ObjectiveTo investigate the general rule, characteristics and risks of adverse drug reaction(ADR) induced by sodium aescinate injection, in order to provide theoretic support for drug Safety in clinical administration. MethodsUse "Sodium aescinate"and"adverse drug reaction"as key words, searching and retrieving references in the following databases as CBM, CNKI, VIP and WanFang Data. 47 references which met the inclusion and exclusion criteria were extracted and analyzed. ResultsThe adverse reactions may involve multiple organs and systems, The most common reactions are phlebitis, allergic reaction,etc. Severe cases can cause anaphylactic shock, renal failure, liver and kidney damage, and skin necrosis. ConclusionIt is important to pay attention to the adverse reactions caused by sodium aescinate when administrating by injection, preventing severe adverse drug reactions from happening, and ensuring the Safety of clinical administration.

Key words: sodium aescinate for injection, adverse drug reaction/event, analysis