Abstract: Objective By reviewing the pharmacological effect, clinical application and adverse reactions of Reduning injection, to provide the basis for safe, effective and reasonable clinical application. Methods The related references in recent years at home and abroad about the pharmacological effect, clinical application and adverse reactions of Reduning injection were collected, summarized and analyzed. Results Reduning injection had obvious antiviral and antibacterial effect, and could effectively increase the body's immune function and improve the disease resistance. Reduning injection has been widely used in respiratory infection and is effective. There were some off-label use reports in which it was used in viral diarrhea, herpes zoster, infantile herpangina, ect. The adverse reactions included allergic reaction, anaphylactic shock, skin and accessories damage, hematuria, and acute laryngeal edema, etc. Conclusion Reduning injection had definitely curative effect on respiratory infection, but there were some off-label clinical use reports. Clinical doctors should strictly and reasonably use reduning injection according to its indications, perfect the countermeasures of adverse reactions in order to improve the safety of drugs.

Key words: Reduning injection, pharmacological effect, clinical application, adverse reactions