Abstract: ObjectiveTo standardize the behaviour of the clinician on how to give proper medicine based on cases. Ensure the safety and the efficacy of the medicine for patients. And bring the pharmacist into full play. MethodsChoose 360 of the cases in 2011 in our hospital to comment and statistically analyze the phenomenon of irrational drug use. Results32.22％ of the cases are substandard, 128 of which are irrational drug use, mainly including irrational ways and amount of giving medicine, not choosing proper medicine, irrational combined medication, repeat to give patients extra medicine, incompatibility and so on. ConclusionThrough the study and the comment on cases, I found that the irrational drug use was very common in our hospital. Pharmacist should report the comments to the clinician to intervene and remind them to ensure the safe and efficient drug use.

Key words: comments on cases, rational use of drugs, drug using analysis