Chinese Journal of Pharmacovigilance ›› 2012, Vol. 9 ›› Issue (4): 239-241.

• Orginal Article • Previous Articles     Next Articles

Retrospective Analysis of the Adverse Reactions of Cefotiam Hydrochloride for Injection in 548 Cases

JIANG Yu-mei1, WANG Li-xia2, YIN Ai-qun3, *   

  1. 1 Branch of Fushan district, Yantai Food and Drug Administration, Fushan district, Shandong Yantai 265500, China;
    2 Yantai Chinese medicine hospital, Shandong Yantai 264000, China;
    3 Yantai Adverse Drug Reaction Monitoring Center of Shandong province, Shandong Yantai 264000, China
  • Received:2011-12-08 Online:2012-04-10 Published:2015-08-10

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Abstract: Objective To investigate the adverse reactions and characteristics of cefotiam hydrochloride for injection in clinical practice. Methods A retrospective analysis was conducted on the 548 reported cases with the adverse reactions of cefotiam hydrochloride for injection collected by Shandong Adverse Drug Reaction(ADR) Monitoring Center since 2006 in Shandong province. Results Skin and its appendages lesions(59.49%) and gastrointestinal system damages(14.60%) were the most common adverse reactions of cefotiam hydrochloride for injection, followed by the central and peripheral nervous system damages(10.40%); The ADRs mostly occurred in infants, children and elderly patients. Conclusion It is quite necessary to use cefotiam hydrochloride strictly and rationally in clinical practice to reduce the occurrence of the ADRs.

Key words: Cefotiam Hydrochloride for injection, adverse drug reactions, analysis