Abstract: Objective To provide reference for clinical rational drug use, the tumor patients's adverse drug reacton(ADR) occurrence and characteristics in our hospital were analyzed. MethodsIn this paper, 164 cases of patients with anti-tumor drug adverse reaction reports were retrospective analyzed on the age, sex, administration way, drug classes and clinical manifestations. ResultsThe results showed that adverse drug reacton mainly happened in the 40 years and old tumor patients. Cytotoxic drugs take the highest incidence. The clinical manifestations of adverse drug reacton in gastrointestinal reaction is given priority, followed by bone marrow inhibition. ConclusionAdverse drug reacton monitoring and reporting work which ensure patients safely use their drugs is the medical staff, especially the clinical pharmacists important task.

Key words: antitumor drugs, adverse drug reacton, rational drug use