Abstract: Objective To investigate the antipsychotic-induced adverse drug reaction/event(ADR/ADE), and provide advice for the rational use of drugs. Methods To conduct a statistical analysis based upon the information from 160- inpatients with ADR/ADE which were reported from January 2007 to March 2010 in my hospital such as gender, age, dosage regimen, drug combination, etc. Results ADR/ADE is likely to be reported in various ages section during inpatients, particularly those are 30~60 years old. It involves seven systems, will mainly cause the central nervous system damage and hepatic dysfunction. Among those drug reported to have adverse reaction, there are more atypical antipsychotics reported than typical antipsychotics. Conclusion Medical institutions should pay attention to antipsychotic-induced adverse reactions and rational use of it.

Key words: antipsychotic drug, nervous system, adverse drug reaction/event(ADR/ADE)