Abstract: Objective In the first quarter of 2010 hospitalized patients in clinical use of antimicrobial agents, to provide a basis for further developing intervention to promote the rational use of drugs. Methods Investigation and monitoring all that day in patients with antibiotics usage; by about 25 percent of randomly selected offices of physician information and electronic patient records, from various angles to antimicrobial drugs used by performing a comprehensive analysis of the data; for part of the date of sampling department monitoring all hospitalized patients, the survey on the use of antibiotics. Results In my hospital antibiotic overall usage is 60.88%; antibacterial drugs to monotherapy, 47.57%; combined mainly concentrated in the second with 32.04%; Institute for pathogens check and drug susceptibility testing ratio is low, only 27.18%. Sampling department use of antibiotics to β-lactam, cephalosporin most high frequency; restrictions on the use of varieties use too much, too high a frequency, the proportion is too large, transplant division special use of antimicrobial agents rates highest for 19.50%; combined usage is high, mostly in the second with the primary; pathogens check and drug susceptibility testing. Conclusion sIn my hospital antibiotic overall usage is high, should be considered fair use, is still a need to intensify the use of antimicrobial agents in the management and super-vision.

Key words: inpatients, antibacterial drugs, irrational use, survey and analysis